Due to insufficient knowledge of the specifics of creative industries, entrepreneurial ventures of young people increasingly result in failure, or even in non-starting an entrepreneurial venture at all because of the risks it entails. The purpose of this thesis is to identify the obstacles that young entrepreneurs face when starting a business and which hinder them in achieving successful business. Thorough research has been performed as well as analysis of support programs for young entrepreneurs, and also research of knowledge, skills and competencies needed to achieve a successful venture. Therefore, in order to detect and identify more clearly obstacles to entrepreneurship in the fashion industry, examples of good and bad practice of entrepreneurs are presented here, including semi-structured interview with 5 entrepreneurs from the fashion industry. The results of the research show that although there are numerous support institutions and various grants to finance the venture, entrepreneurs are still not sufficiently informed, which leads them to consider the support from the state to be insufficient. In addition, creative workers lack the entrepreneurial education they need to be more knowledgeable in business, which leads to the problems with market entry, negotiation skills, promotion, administration, and the like. The results of the thesis can help young entrepreneurs and all those who want to take chance at entrepreneurship in creative industries, referring to the obstacles they may encounter when entering entrepreneurship, the obligation to develop basic knowledge, skills and competencies and also practical recommendations that would facilitate not only starting an entrepreneurial venture in the fashion industry, but also its future development and sustainability.