Controlling as a modern concept of business management and decision-making in the modern business environment is gaining more and more importance during the realization of entrepreneurial ventures that strive to ensure economic and financial effects and the vitality of the company over a long period of time. Human resources are the main bearers of the realization of entrepreneurial ventures and a key decision-making factor. Therefore, special attention should be paid to the principle of coordination and the principle of integration of human resources together with other potentials of the company in order to ensure the necessary prerequisites for achieving success. The idea for a joint business venture - Tourist package arrangement in the Neretva valley arose from the lack of tourist content in the Neretva valley and the insufficient connection of local entrepreneurs. Their cooperation through the implementation of joint business ventures could contribute to the enrichment of the tourist offer, which would make better use of the great tourist potential of the mentioned region. Consequently, economic and financial benefits and social benefits for local entrepreneurs and the entire local community would be ensured. Precisely by achieving the desired synergistic effect of association, the prerequisites for achieving sustainable growth and development not only of local entrepreneurs, but also of the Neretva region as a whole would be created. For this purpose, primary and secondary research was conducted and cognitive scientific research methods were dominantly used. The primary research related to the application of the method of semi-structured in-depth interviews with small and medium-sized local entrepreneurs from various branches of the economy and employees from the local administration. The conducted research showed that: (1) there are specificities of small and medium-sized entrepreneurship within the specificities of the Neretva Valley, (2) cooperation between HR experts and HR controllers has a key role in the realization of joint business ventures from various economic activities, such as the Tourist package arrangement in Neretva valley, (3) joining in a joint entrepreneurial venture contributes to the growth and development of local entrepreneurs and the local community and (4) that the cooperation of HR experts from different economic activities can be achieved through collaborative projects and the use of the concept of project management.