Slavonia County is among the economically least developed counties in the Republic of Croatia. This undergraduate thesis examined and explained how the economy and entrepreneurship in the county have developed over last 15 years and what the possibilities for further progress are. Development has been greatly influenced by crises that left their mark on the economy of the county as well as on entrepreneurs and their companies, which could not operate normally. Development is influenced by certain factors that help or hinder the economy. These factors are the economic opportunities taking place in the county, the transport connections, and the available resources throughout the county. Empirical research was conducted for the thesis, which was divided into two parts. The first part focused on thirty surveyed entrepreneurs and their views on business practices, progress, and problems they face. The second part focused on three interviewed experts who are in management positions within institutions related to the economy of the county (Požega Polytechnic, Plink Business Incubator, Pozega County Chamber - Croatian Chamber of Commerce). Research has shown various factors that influence the growth and development of entrepreneurship and the economy, as well as different opinions about the possibility of progress. At the end of the work, the results showed how much progress has been made, what the biggest problems for the economy and entrepreneurship are, and further prospects for development in Požega-Slavonia County.