With the intensification of globalization in the 20th century, there have been a number of changes in the business world. Companies are expanding to other countries and developing their business on other continents. According to that, there are also changes in the structures and methods of cooperation within the organizations themselves. In international business, there is a cross-cultural work environment for employees and cross-cultural human resource management is becoming the norm of the global companies. It establishes the necessary rules for the normal functioning of the organization and its employees, thus ensuring safety and a work environment without discrimination. In addition to the HRM department, cross-cultural team leaders have an important role to play in leading, managing and encouraging teams to embrace diversity as well as to grow and develop. The objectives of this paper are to explain the importance and role of the human resources department in international companies, to examine the challenges faced by the heads of human resources departments in managing such teams and to examine employees' perceptions of the challenges of working in international teams. For the purpos of the paper, a survey was conducted on a sample of 102 Danfoss employees (especially the Climate Solutions department) and interviews with two human resources managers. The results showed that employees face certain obstacles in a multicultural work environment, especially misunderstandings due to misinterpreted nonverbal communication. However, they also believe that these differences contribute to personal and business growth and progress and are an advantage, rather than disadvantage, of working with different cultures. Human resources managers agree with this, pointing out the adjustment of various laws and rules in each country as the biggest challenge.